Features of the macro and microscopic structure of the lungs of a mature rabbit – Oryctolagus cuniculus L. 1758

The macro- and microscopic structure of the lungs mature rabbits – Oryctolagus cuniculus L., 1758 European rabbit was studied. This work performed using comprehensive research methods: anatomical, organometric, histological histometric. carried out in conditions laboratory pathomorphology Department Anatomy Histology. scientific on subject Histology Polissya National University theme: “Development, morphology histochemistry animal organs normal pathological”, according to state registration number № 0113V000900. morphological studies followed basic rules Good Laboratory Practice GLP (1981), provisions “General Ethical Principles Animal Experiments”, adopted by First Congress Bioethics (Kyiv, 2001) requirements for “Rules carrying with experimental animals”, approved order Ministry Health 281 November 1, 2000 “On measures further improve organizational forms use animals”. material histomorphological were pieces selected from clinically healthy adult (n = 5). Slices made paraffin blocks a sled microtome MS–2. thickness sections did not exceed 8–12 μm, which then stained hematoxylin eosin Van Gizon study morphofunctional activity cells tissues respiratory tract. Histometric specimens microscope “Micros” digital camera at magnification × 100–1000. Studies have shown that macroscopically reflection shape thoracic cavity, gradually expands ventrally. right left are surrounded pleural sacs. cavities both test animals interconnected. Organometry showed absolute lung mass is 18.05 ± 1.32 g, relative 0.624 0.013 %. histoarchitectonics formed lobes. department represented set acinuses. latter bronchioles, alveolar passages, sacs alveoli form tree. results morphometric (respiratory) part occupies 39.6 0.62 %, connective tissue base, respectively, 58.5 1.27 average volume alveoli, divided into small, medium large, 42.3 4.35 thousand μm3. Thus, great general biological importance, as they an important criterion objective assessment differential diagnosis diseases various origins.